Which drug is used in hepatoprotective drug?
Silymarin, a flavonolignan from ‘milk thistle’ (Silybum marianum) plant is used almost exclusively for hepatoprotection and amounts to 180 million US dollars business in Germany alone.
What is hepatoprotective activity?
In vivo and well as ex vivo test models are used to evaluate hepatoprotective activity. These systems measure the ability of the drug to prevent or cure hepatic toxicity (induced by different hepatotoxins) in cellular cultures, organs or in experimental animals (rats, mice, etc.) respectively.
What foods are hepatoprotective?
The present review had as its objective the collecting of data based on research conducted into some fruits (grapefruit, cranberries, and grapes) and plants [cactus pear (nopal) and cactus pear fruit, chamomile, silymarin, and spirulina], which are consumed frequently by humans and which have demonstrated …
Which is a potent hepatoprotective?
Among them, ampelopsin C and the mixture of vitisin A and cis-vitisin A were found to be powerful hepatotoxins.
What drugs cause hepatotoxicity?
The 10 most frequently implicated drugs were: amoxicillin-clavulanate, flucloxacillin, erythromycin, diclofenac, sulfamethoxazole/Trimethoprim, isoniazid, disulfiram, Ibuprofen and flutamide [12,13,14,21].
What does hepatotoxicity mean?
Toxic liver disease is damage to your liver. It’s also called hepatotoxicity or toxic hepatitis. It can cause serious symptoms or liver damage if you don’t get help. Medications, herbal supplements, chemicals, solvents, and alcohol are all possible causes of hepatotoxicity.
Where is the live located?
Anatomy of the liver The liver is an organ located in the upper right part of the belly (abdomen). It is beneath the diaphragm and on top of the stomach, right kidney, and intestines.
Which of the Phytoconstituents are hepatoprotective in nature?
These hepatoprotective plants have the phytoconstituents such as phenyl compounds, coumarins, essential oils, monoterpenoids, diterpenoids, triterpenoids, steroids, alkaloids and other nitrogenous compounds.
Which of these Phytoconstituent is hepatoprotective in nature?
Which of the following is a potent hepatoprotective and is widely used to treat liver disorders?
graveolens have been widely used in traditional medicine for the treatment of liver and spleen disorders, jaundice [7], rheumatism, gout, and other inflammatory diseases [8, 9]. The hepatoprotective activity of the methanolic extract of A.
Which antibiotic is hepatotoxic?
Frequency and characteristics of antibiotic-induced hepatotoxicity
| Antibiotic . | Incidence . | Liver injury . |
|---|---|---|
| Isoniazid | 1%–10% of patients | hepatocellular necrosis |
| Pyrazinamide | 6%–20% of patients | centrolobular cirrhosis and cholestasis |
| Rifampicin | <2% of patients | cholestatic hepatitis |
| Streptomycin | no hepatotoxic potential |