What does low grade abnormality mean?

Low-grade squamous intraepithelial lesion (LSIL) is a common abnormal result on a Pap test. It’s also known as mild dysplasia. LSIL means that your cervical cells show mild abnormalities. A LSIL, or abnormal Pap result, doesn’t mean that you have cancer. The tissue that covers your cervix is made up of squamous cells.

Can low grade cells be cancer?

Low-grade squamous intraepithelial lesions usually go away on their own without treatment, but sometimes they can become cancer and spread into nearby tissue. Low-grade squamous intraepithelial lesion is sometimes called mild dysplasia. Also called LSIL.

Should I worry about CIN 3?

CIN 3 is not cancer, but may become cancer and spread to nearby normal tissue if not treated. Treatment for CIN 3 may include cryotherapy, laser therapy, loop electrosurgical procedure (LEEP), or cone biopsy to remove or destroy the abnormal tissue. CIN 3 is sometimes called high-grade or severe dysplasia.

Does low grade dysplasia mean cancer?

Mild dysplasia, called low-grade intraepithelial lesion (LSIL) is one type. Moderate or severe dysplasia, called high-grade intraepithelial lesion (HSIL) is another type of dysplasia. LSIL and HSIL may or may not become cancer.

How fast does LSIL progress?

Untreated LSIL can progress in 13% of cases to HSIL during 2 years of monitoring (9,10). Women infected with HPV 16 have a transition of LSIL into HSIL in 9% of cases.

Does LSIL mean you have HPV?

Low-Grade Squamous Intraepithelial Lesions (LSIL) means that there are low-grade changes that are usually caused by an HPV infection. Your health care provider will likely ask you to come back for additional testing to make sure that there are not more serious (high-grade) changes.

How many abnormal Pap smears are cancer?

Abnormal Pap tests are very common. In fact, of the 3 million women with abnormal Pap tests each year, less than 1% (13,240 cases) will be diagnosed with cervical cancer.

Can you get abnormal cells without HPV?

No HPV found (hrHPV negative) If you don’t have HPV, it is highly unlikely that you will have any abnormal cervical cells. Even if you did, it would be extremely unlikely that they would cause a problem. You will simply be called back for screening again in 3 – 5 years’ time (depending on your age).

Can CIN 3 heal itself?

More than 90% of infections are spontaneously cleared by the immune system within one year without treatment. Approximately 60% of CIN 1 lesions regress without treatment and less than 1% progress to cancer. However, it is estimated that 5% of CIN 2 and 12% of CIN 3 cases will progress to invasive cancer if untreated.

Does CIN 3 have symptoms?

CIN3 may be referred to as severe dyskaryosis or severe dysplasia. Less commonly, it is called carcinoma-in-situ, though this term is rarely used these days. CIN1, 2 and 3 rarely cause any symptoms, such as pain, discharge or bleeding.

How long does it take for dysplasia to turn into cancer?

These conditions are not yet cancer. But if they aren’t treated, there is a chance that these abnormal changes may become cervical cancer. If left untreated, it may take 10 years or more for precancerous conditions of the cervix to turn into cervical cancer, but in rare cases this can happen in less time.

How is low-grade dysplasia treated?

Radiofrequency ablation may be used in patients with low-grade dysplasia. For confirmed low-grade dysplasia without life-limiting comorbidity, the preferred treatment modality is endoscopic therapy. However, an acceptable alternative is endoscopic surveillance every 12 months.