What is Octafluoropropane used for?
Octafluoropropane microbubbles reflect sound waves well and are used to improve the ultrasound signal backscatter. It is used in eye surgery, such as pars plana vitrectomy procedures where a retina hole or tear is repaired.
How is perflutren administered?
Perflutren is given as an infusion into a vein. A healthcare provider will give you this injection just before the start of your echocardiogram. Your heart rate, breathing, blood pressure, oxygen levels, and other vital signs will be watched closely for at least 30 minutes after you receive perflutren.
What is DEFINITY used for?
DEFINITY® is an injectable cardiovascular ultrasound enhancement agent comprised of lipid-coated echogenic microbubbles filled with octafluoropropane gas. Administration of DEFINITY® enhances clinicians’ view of the left ventricle of the heart during an echocardiogram to aid with diagnosis.
How long does DEFINITY stay in your system?
The activated DEFINITY may be used for up to 12 hours from the time of activation, but only after the microspheres are resuspended by hand agitation.
What is optison used for?
Optison is used to obtain a clearer scan of the chambers of the heart, especially of the left ventricle, during echocardiography (a diagnostic test where an image of the heart is obtained using ultrasound).
What is perflutren lipid microsphere used for?
Perflutren lipid microsphere injection is used during an echocardiogram to help diagnose or find problems in the heart. Perflutren lipid microsphere is an ultrasound contrast agent. Ultrasound contrast agents are used to help provide a clear picture during ultrasound.
What is perflutren lipid microspheres injection?
How do you inject DEFINITY?
Instructions
- Vent vial with a needle by placing needle tip in the activated DEFINITY® vial.
- Attach an 18- or 20-gauge unfiltered needle to the 3 mL syringe and place the needle in the vial.
- Invert vial and slowly withdraw 1.3 mL activated DEFINITY® from the middle of the liquid without injecting air into the vial.
What is the difference between Optison and DEFINITY?
Preparation requirements for each of the agents differ: Definity requires activation with a mechanical agitator, Optison requires a resuspension of the bubbles by hand, and Lumason requires mixing and hand agitation.
Does DEFINITY affect the kidneys?
Definity® has been approved in the United States for cardiac indications. Extensive studies of these agents have demonstrated a significant safety profile with no evidence of toxicity to the kidneys, heart or liver.
What are the side effects of DEFINITY?
Common side effects of Definity include:
- injection site reactions,
- back and chest pain,
- headache,
- dizziness,
- nausea,
- flushing,
- fatigue,
- fever,
Is optison a blood product?
Optison is classified by the FDA as a medical imaging drug product; it is not a blood product, even though the microsphere shell is made from a naturally occurring blood protein, albumin.