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In some occasions, you will have to write an essay in the extremely short amount of time on the exam in college or high school. Also, you may be a little bit of a procrastinator, and find yourself in a situation when the paper is due tomorrow morning, and you have not even chosen the topic yet. Even though a last-minute essay cannot look as great as a work prepared successively and carefully within the whole time given, you still have a chance to submit a decent paper. The working process will require your full attention and a lot of effort, even if you are assigned a simple essay. However, if you learn the next few tips, the essay writing will seem significantly easier and feasible even when you are short on time.

Firstly, clean up your working space to get started. Make sure you have everything you need on the table, take a pen, a few sticky notes, your laptop, and read through the assignment requirements. In case no prompt is given, search for good essay topics, and pick a few uncommon and interesting ones you will be able to write about. Making a final choice, think which topic is the most relevant to your current studies and will not take too much to research.

Afterwards, look for the most trustworthy sources or the ones you are certainly allowed to use. If you are not sure, access the online library or any free services where you can look for the books and articles for your essay. Use sticky notes to write down the information and put them in front of you to see how much data has been gathered and if you need to continue researching. Reread these notes from time to time and cross out the info you do not find relevant anymore.

When you have the data you need to produce a quality work, it is crucial to think about the structure of the future paper. If you are not sure how to write an essay outline properly, check what your essay type is first. Each type is organized differently, so you need to look up the structure every time you are given an essay homework. You can also search for an example of the essay on your topic, and adhere to its outline. No matter what kind of essay you are going to write, it is important to start with a thesis statement. It should declare what problem you will review in the paper, and which facts or arguments you will use to do it professionally. As these arguments will be discussed in the main part of the essay, outline the body paragraphs and put down a few sentences with the rough description of each paragraph. Think of the way you will engage the reader in the introduction, and which thought will be conclusive for the paper. When the direction of the work is clear from the outline, use it to draft the first version of the essay.

If you are not used to model essay writing, do not worry - your draft should not necessarily look like a masterpiece. It is only the depiction of your thoughts, and as you will have them written down, it will be easier to create a good essay. There is no best way to write an essay, so trust the working methods you usually use. You may like taking short breaks once in a few minutes, or write everything in one sit - just make sure to keep the focus on writing and avoid the urge to call a friend or watch something online. Thus, you will finish the paper faster, and will not feel guilty for engaging in other activities afterwards.

Do not forget to go through the essay a few times after the completion. Everyone makes typos and mistakes by accident, but it is about you to find and fix them before your teacher does. If you need help with an essay editing, try asking a friend or a family member to read and analyze your work. Also, you can order editing services in case your paper needs to be perfectly polished so that you can submit an ideal essay and get an excellent grade.

As these steps are simple to follow, you will not have any problems coping with an essay on time. Try the whole procedure at least once, and you will not have to use any other tips preparing an essay paper during your studies!

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What is the function of MCP?

What is the function of MCP?

MCP-1 (Monocyte chemoattractant protein-1), also known as Chemokine (CC-motif) ligand 2 (CCL2), is from family of CC chemokines. It has a vital role in the process of inflammation, where it attracts or enhances the expression of other inflammatory factors/cells.

What is MCP cytokine?

Chemokines (chemotactic cytokines) are small heparin-binding proteins that constitute a large family of peptides (60–100 amino acids) structurally related to cytokines, whose main function is to regulate cell trafficking.

Does MCP-1 cause inflammation?

In summary, our data suggest that MCP-1 may be a necessary component of the inflammatory response required for adipose tissue protection, remodeling, and healthy expansion in the FVB/N strain in response to HFD feedings.

What produces CCL2?

CCL2 (monocyte chemoattractant protein-1, MCP-1) is a potent chemokine for monocytes, and a variety of other immune cells. Its receptor is CCR2, which is expressed at high levels on monocytes. CCL2 is produced by osteoblasts in response to PTH and proinflammatory cytokines.

Is MCP-1 proinflammatory cytokine?

MCP-1 (also known as C-C chemokine motif ligand 2, CCL-2) is a proinflammatory cytokine that is up-regulated in human myometrium during labor.

What is MCP in blood?

However, whether blood PTX3 level can be used as an indicator of clinical RA disease activity is unknown. Another new mediator of inflammation, monocyte chemotactic protein-1 (MCP-1), is chemotactic for monocytes, basophils, T cells, and mast cells [19].

What is MCP in inflammation?

Background: Monocyte chemoattractant protein 1 (MCP-1) is known to be an important chemokine for macrophage recruitment. Thus, targeting MCP-1 may prevent the perturbations associated with macrophage-induced inflammation in adipose tissue.

What is CCL2 a marker of?

CCL2 is implicated in pathogeneses of several diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis.

What is the difference between chemokines and cytokines?

Cytokines are an exceptionally large and diverse group of pro- or anti-inflammatory factors that are grouped into families based upon their structural homology or that of their receptors. Chemokines are a group of secreted proteins within the cytokine family whose generic function is to induce cell migration [2, 3].

What produces MCP-1?

MCP-1 can be produced by a variety of cell types, such as macrophages, neutrophils, fibroblasts, endothelial cells, and epithelial cells.

Is CCL2 pro or anti inflammatory?

In yet another study, it was reported that granulocyte-macrophage colony-stimulating factor (GM-CSF) enhanced wound healing in diabetes by upregulating pro-inflammatory cytokines [29]. Interestingly, CCL2 was one of the upregulated pro-inflammatory cytokines.

Is histamine a cytokine?

Histamine acts as a pro-TH2, anti-TH1 mediator during TH differentiation by modulating cytokine production by antigen-presenting cells (APC). Furthermore, it hampers TH2 activity of differentiated cells via H2 receptors which are preferentially expressed on TH2 cells.

What is MCP-1 antibody?

* Avoid repeated exposure to skin. MCP-1 Antibody detects endogenous levels of total human MCP-1 protein. Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Cys35 of human MCP-1. Antibodies were purified by protein A and peptide affinity chromatography.

How does the human MCP-1 solid-phase sandwich assay work?

The assay will exclusively recognize both natural and recombinant Hu MCP-1. The Human MCP-1 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate.

What is the role of MCP1 in psoriasis?

MCP-1 is secreted by a variety of cell types in response to pro-inflammatory stimuli and was originally described for its chemotactic activity on monocytes. This activity has led to studies demonstrating its role in diseases characterized by monocyte infiltrates such as psoriasis (5), rheumatoid arthritis (6) and atherosclerosis (7).

What is recombinant MCP1 AA?

Recombinant fragment corresponding to Rat MCP1 aa 1-73 (N terminal). The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.