What are the contraindications of haloperidol?
HALDOL (haloperidol) is contraindicated in patients with:
- Severe toxic central nervous system depression or comatose states from any cause.
- Hypersensitivity to this drug – hypersensitivity reactions have included anaphylactic reaction and angioedema (see WARNINGS, Hypersensitivity Reactions and ADVERSE REACTIONS).
What are the contraindications of clozapine?
Clozapine is contraindicated in patients with serious hypersensitivity reactions to clozapine or any component of the formulation….Contraindications
- Neutropenia (due to the risk of agranulocytosis)
- Orthostatic hypotension.
- Seizures.
- Myocarditis.
- Dementia (risk of a cardiovascular event)
What are the contraindications of olanzapine?
The following conditions are contraindicated with this drug….Conditions:
- breast cancer.
- diabetes.
- a high prolactin level.
- high cholesterol.
- high amount of triglyceride in the blood.
- excessive fat in the blood.
- dehydration.
- overweight.
What drugs are Butyrophenones?
Butyrophenones (haloperidol and droperidol) constitute the main class of typical antipsychotic medications recommended for an undifferentiated patient with acute agitation in the ED.
What is the indication of haloperidol?
Haloperidol is indicated for the treatment of the manifestations of several psychotic disorders including schizophrenia, acute psychosis, Tourette syndrome, and other severe behavioural states.
Is haloperidol contraindicated in heart failure?
Haloperidol should be administered cautiously to patients with severe cardiovascular disorders because of the possibility of transient hypotension and/or precipitation of anginal pain.
What is the most serious risk related to clozapine treatment?
The most severe and potentially life-threatening clozapine-related blood dyscrasias is neutropenia, which may eventually develop into clozapine-induced agranulocytosis or granulocytopenia.
What is the most serious side effect of clozapine?
Seek immediate medical attention if any of these rare but very serious side effects occur: severe dizziness, fainting, mental/mood changes, difficulty breathing with exercise, swollen legs/feet, sudden weakness, pain/redness/swelling of the arms/legs, chest pain, persistent nausea/vomiting, stomach/abdominal pain.
What is the major side effect of olanzapine?
Drowsiness, dizziness, lightheadedness, stomach upset, dry mouth, constipation, increased appetite, or weight gain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Dizziness and lightheadedness can increase the risk of falling.
What is olanzapine used for?
Olanzapine is used to treat schizophrenia. It may also be used alone or with other medicines (eg, lithium or valproate) to treat mania or mixed episodes that is part of bipolar disorder (manic-depressive illness).
What do butyrophenones do?
Butyrophenones work primarily by blocking dopamine-mediated synaptic neurotransmission by binding to dopamine receptors. In addition to significant antidopaminergic action, butyrophenones also possess anticholinergic, α-adrenergic blockade, and quinidine-like effects.
What is the meaning of butyrophenone?
/bu·ty·ro·phe·none/ (bu″tĭ-ro-fe´nōn) any of a class of structurally related antipsychotic agents, including haloperidol. butyrophenone. n. Any of a group of antipsychotic drugs, such as haloperidol, administered in the treatment of schizophrenia and other psychiatric disorders.
What are the side effects of butyrophenones?
Butyrophenones are particularly liable to produce unwelcome side effects, the most alarming being an acute dystonic reaction and in the longer term tardive dyskinesia. It is wise to start with a small dose of haloperidol, for instance 1.5 mg three times daily.
What is the mechanism of action of butyrophenones?
Butyrophenones induce a state of apathy and mental detachment in patients with dysharmonious brain function. They inhibit dopamine-mediated neurotransmission in the cerebrum and basal ganglia.
What is butyrophenone haloperidol used for?
The butyrophenone haloperidol is the neuroleptic of choice in the treatment of delirium in critically ill patients. Because it is not a respiratory depressant, haloperidol can be used in patients with agitation and compromised pulmonary function.