What are the most common side effects of daptomycin?
More common
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site.
- difficulty having a bowel movement.
What should I monitor with daptomycin?
Patients receiving daptomycin should be monitored for the development of muscle pain or weakness. Consideration should be given to temporarily suspending agents associated with rhabdomyolysis.
What does daptomycin do to your body?
Daptomycin belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections. This medicine is to be given only by or under the direct supervision of your doctor.
Is daptomycin a strong antibiotic?
Daptomycin (Cubicin) is an injectable antibiotic used to treat serious bacterial infections of the skin and underlying tissues and infections that have entered the bloodstream. Daptomycin (Cubicin) is usually used for complicated and serious infections since it is a strong antibiotic.
Is daptomycin a high risk medication?
This medication is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria. This medication is not recommended for use in children younger than 12 months due to possible risk of serious side effects.
Is daptomycin a high risk drug?
Elderly patients are at an increased risk of daptomycin toxicity due to age-related changes in renal function or factors that may enhance the exposure to the medication. However, no dosage adjustments are recommended for patients with a creatinine clearance greater than 30 mL/min.
When should daptomycin be discontinued?
Daptomycin should be discontinued in patients with symptoms of muscle pain or weakness whose CPK levels exceed 1000 U/L (~ 5x ULN), or in patients without symptoms whose CPK exceeds 10x ULN.
Can daptomycin cause insomnia?
aureus bacteremia/endocarditis (receiving 6 mg/kg CUBICIN) are displayed in Table 7….S. aureus Bacteremia/Endocarditis Trial In Adults.
| Adverse Reaction* | Adult Patients n (%) | |
|---|---|---|
| Sweating increased | 6 (5%) | 0 (0%) |
| Psychiatric disorders | ||
| Insomnia | 11 (9%) | 8 (7%) |
Can daptomycin cause liver damage?
Conclusion: Although hepatic abnormalities caused by daptomycin are rare, a handful of cases with daptomycin-induced liver injury have been reported in the literature. Of note, in most cases, patients on daptomycin therapy developed liver damage with elevations in CK levels.
Is daptomycin hard on the kidneys?
Statistical analysis. In a previous study [17], the incidence of renal dysfunction was estimated at 12% with daptomycin and 35% with standard therapy. However, a higher incidence of renal failure was expected in ICU population, as much as twice the incidence observed in the reference study [10, 19].
Does daptomycin cause elevated liver enzymes?
What are the side effects of daptomycin?
Along with its needed effects, daptomycin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Anemia and thrombocytopenia have also been reported during postmarketing experience. Common (1% to 10%): Anemia.
Does daptomycin affect creatine phosphokinase levels?
Daptomycin is associated with an increased incidence of myopathy and rhabdomyolysis. There have been cases reported in patients with and without acute renal failure. Therefore weekly monitoring of creatine phosphokinase (CPK) levels is recommended in patients receiving daptomycin therapy.
How is daptomycin monitored in healthcare workers?
Healthcare workers, including intensivists, infectious disease specialists, internists, and nurse practitioners who prescribe daptomycin, should monitor the patient to ensure safe administration of the medication. Baseline renal function tests are recommended to assess renal impairment and the necessity of dosage adjustments.
How long should I take daptomycin for?
daptomycin may cause false results with certain medical tests. Tell any doctor who treats you that you are using daptomycin. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Some infections must be treated for up to 6 weeks.