What is Peripapillary choroidal neovascular membrane?

Peripapillary choroidal neovascular membranes (PCNM) are defined as a collection of new choroidal blood vessels, any portion of which lies within one disc diameter of the nerve head.

What does choroidal neovascularization mean?

Choroidal neovascularization (CNV) involves the growth of new blood vessels that originate from the choroid through a break in the Bruch membrane into the sub–retinal pigment epithelium (sub-RPE) or subretinal space. CNV is a major cause of visual loss.

How is CNV diagnosed?

The ophthalmologist can detect CNV using a combination of techniques. First, during the dilated eye exam, she/he may see a blister of fluid or bleeding in the retina. Then, using specialized imaging called optical coherence tomography (OCT), a cross-section picture of the retina is obtained.

Can CNV cause blindness?

Choroidal neovascularization (CNV), which often causes severe vision loss and eventually blindness, is a common pathologic change that may occur in more than 30 ocular diseases1. Age-related macular degeneration (AMD) is the most common cause of CNV in the elderly2.

What does Peripapillary mean?

Medical Definition of peripapillary : situated around the optic papilla.

Can choroidal neovascularization be cured?

Choroidal neovascularization (CNV) is the medical term for growth of new blood vessels beneath the eye’s retina (subretinal). It can be painless, but can lead to macular degeneration, a major cause of vision loss. This condition may respond to treatment, while being incurable.

Is choroidal neovascularization the same as macular degeneration?

Choroidal neovascularization (CNV) is the growth of pathologic new blood vessels and is the most important sequella of age-related macular degeneration (AMD).

Why does choroidal neovascularization occur?

CNV is a common cause of vision loss. The most common cause of CNV is from age-related macular degeneration. In younger patients, neovascularization occurs primarily in the presence of cracks within the retinal macular tissue known as lacquer cracks when associated with myopic degeneration and extreme myopia.

What does CNV look like on Oct?

Well-defined classic CNV appears on OCT as hyperreflective areas in contact with or in front of the RPE; the pathology may be dome-shaped or appear as a thin formation (fusiform or nodular) (Figure 4).

What is treatment for CNV?

Currently, the treatment of choice for CNV secondary to exudative AMD is intravitreal anti-VEGF therapy. A reduced biological response to both intravitreal ranibizumab and bevacizumab has been reported by several authors. A distinction between tachyphylaxis and drug tolerance should be made.

Can CNV be cured?

Where is the Peripapillary region?

The peripapillary region was defined as a 700-μm-wide elliptical annulus extending from the optic disc boundary. An en face angiogram of the retinal circulation was obtained by the maximum flow (decorrelation value) projection from the inner limiting layer to retinal epithelial pigment.