What is the difference between exogenous and endogenous cholesterol?
1). In the endogenous path- way, cholesterol is synthesized by the liver and extra- hepatic tissues and secreted into plasma, whereas the intestine is the primary site of the exogenous pathway of dietary cholesterol uptake[1–3].
What are key differences between the exogenous pathway and endogenous pathway?
The main difference between exogenous and endogenous antigens is that the exogenous antigens enter the body from the outside whereas the endogenous antigens are generated inside the body. Exogenous and endogenous antigens are the two main types of antigens in the body. They are classified based on the origin.
What is the endogenous pathway of lipoprotein metabolism?
The endogenous lipoprotein pathway begins in the liver with the formation of VLDL. The triglycerides carried in VLDL are metabolized in muscle and adipose tissue by lipoprotein lipase releasing free fatty acids and IDL are formed.
What are exogenous and endogenous lipids?
Lipids are body fats that are either synthesized within cells (endogenous lipids) or derived from dietary fat (exogenous lipids).
How much cholesterol is exogenous?
Dietary cholesterol or “exogenous” cholesterol accounts for approximately one-third of the pooled body cholesterol, and the remaining 70% is synthesized in the body (endogenous cholesterol).
What is exogenous lipid?
Exogenous pathway for lipid metabolism: Dietary cholesterol and fatty acids are absorbed. Triglycerides are formed in the intestinal cell from free fatty acids and glycerol and cholesterol is esterified. Triglycerides and cholesterol combine to form chylomicrons.
What is the difference between exogenous and endogenous antigens?
Endogenous antigens are antigens found within the cytosol of human cells such as viral proteins, proteins from intracellular bacteria, and tumor antigens. Exogenous antigens are antigens that enter from outside the body, such as bacteria, fungi, protozoa, and free viruses.
What is the exogenous pathway?
The exogenous pathway is utilized by specialized antigen-presenting cells to present peptides derived from proteins that the cell has endocytosed. The peptides are presented on MHC class II molecules. Proteins are endocytosed and degraded by acid-dependent proteases in endosomes; this process takes about an hour.
What is exogenous pathway?
What is exogenous pathway of lipid metabolism?
What are the exogenous lipids?
What are endogenous triglycerides?
Endogenous Pathway The liver constantly synthesizes triglycerides by utilizing as substrates free fatty acids and carbohydrates; these endogenous triglycerides are secreted into the circulation in the core of very-low-density lipoprotein particles (VLDL).